Characterizing Immunoglobulin Repertoire from Whole Blood by a Personal Genome Sequencer
نویسندگان
چکیده
منابع مشابه
Characterizing Immunoglobulin Repertoire from Whole Blood by a Personal Genome Sequencer
In human immune system, V(D)J recombination produces an enormously large repertoire of immunoglobulins (Ig) so that they can tackle different antigens from bacteria, viruses and tumor cells. Several studies have demonstrated the utility of next-generation sequencers such as Roche 454 and Illumina Genome Analyzer to characterize the repertoire of immunoglobulins. However, these techniques typica...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0075294